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Legal status

Missouri

No legal psilocybin accessFAQ →Bill tracker →Español →Providers and retreats in Missouri →Reviewed October 2026

What psychedelic access is allowed in Missouri?

No legal psilocybin access. Access depends on the substance and setting; this is not blanket permission to possess, buy or sell psychedelics.

Official source: Missouri, official statutes and legislature →

Psilocybin is a Schedule I controlled substance under Missouri law. Possession, sale and facilitation are criminal offenses; clinical trials are the only lawful route.

Current law

Missouri controlled substances law

  • Possession or sharing psilocybin can be prosecuted
  • Clinical trials are the only lawful route
  • Ketamine can be prescribed off-label by licensed clinicians

Providers and their documented services

5 listed

Alive Health & Wellness

Kirkwood, MO

Listed, not verified

Documented services

Ketamine clinic

Sources

Full profile →

Ascend Wellness Center

Lee's Summit, MO

Listed, not verified

Documented services

IV ketamine infusion therapy

Sources

Full profile →

InVita Health & Wellness

St. Louis, MO

Listed, not verified

Documented services

Ketamine therapy

Sources

Full profile →

Midwest Institute for Hearts and Minds

St. Louis, MO

Listed, not verified

Documented services

Ketamine clinic

Sources

Full profile →

Morpheus IV Hydration & Infusion Center

Columbia, MO

Listed, not verified

Documented services

IV ketamine infusion therapy

Sources

Full profile →