Ketamine therapy in Colorado and Denver

Yes, with a prescription. Ketamine is a prescription medicine that licensed clinicians use off-label for depression and other conditions; Spravato (esketamine) is FDA-approved for treatment-resistant depression and is given only in certified clinics.

Ketamine is separate from Colorado's natural medicine program. That program licenses healing centers for psilocybin; ketamine clinics operate under ordinary medical licensing instead.

Denver-area clinics we checked post $250 to $450 per mental-health treatment, and some charge a separate first assessment. Infusions are usually self-pay; Spravato is often covered by insurance after prior authorization.

Ask who supervises treatment, how you are screened and monitored, what the price includes, and whether therapy or integration support is offered. Listings below link to each clinic's own website so you can check details yourself.